Multicomponent UV-Visible Analysis in Tablet Dissolution Testing

Simultaneous infrared spectroscopic imaging and visible photography to monitor tablet dissolution and drug release

A method to study tablet dissolution simultaneously by Fourier transform infraredattenuated total reflection (FTIR-ATR) imaging and macro-photography is described. Such a combined approach appeared important as the results of macro-photography, which have been provided by a number of authors, led to contradictory interpretations. The macro-photographs of a pharmaceutical tablet during exposure ...

UV-Visible Spectrophotometric Method Development and Validation of Assay of Paracetamol Tablet Formulation

It is the branch of science dealing with the study of interaction between Electromagnetic radiation and matter. It is a most powerful tool available for the study of atomic and molecular structure/s and is used in the analysis of wide range of samples. Optical spectroscopy includes the region on electromagnetic spectrum between 100 Å and 400 μm. The regions of electromagnetic spectrum are shown...

Basic UV/Visible Spectrophotometry

Electric current density imaging of tablet dissolution.

The Electric current density imaging technique (CDI) was used to monitor the dissolution of and ion migration from tablets of different acids in agar-agar gel. Conventional MRI cannot monitor these processes, since it can only show changes in the size of the tablet during the dissolving process. CDI traces the dissolved ions thanks to changes in conductivity.

In-Situ Dissolution Testing Using Different UV Fiber Optic Probes and Instruments

Introduction: Fiber optic technology for dissolution testing has been a topic of interest for many researchers for some years. Josefson, Johansson, and Tortensson 1 published early research in this field in 1988. They explored the feasibility of using UV fiber optics for in-situ dissolution and to overcome sample turbidity interference without filtration. In 1993, Brown and Lin 2 used a single ...